PatientSpotlight, by PanaceaIntelPatientSpotlight
SignalNEWMay 5, 20261 min read

Post-stroke spasticity therapy options widen past oral baclofen

Botulinum toxin maturity, intrathecal baclofen pump access, and emerging novel mechanism programs are reshaping post-stroke spasticity management.

Post-stroke spasticity has been an oral antispastic and physical therapy category for years with botulinum toxin in selected populations. Botulinum toxin use is now well-established with multiple approved formulations and growing real-world data, intrathecal baclofen pump access is widening, and novel mechanism programs (myostatin pathway, alpha-adrenergic, others) are in late-stage trials. The infrastructure question (specialist injection capacity, integrated rehabilitation services) bounds the addressable population.

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