PatientSpotlight, by PanaceaIntelPatientSpotlight

Topic · Immunology

Drug development

Coverage of the development arc of new therapies - trial design, endpoint selection, accelerated vs traditional approval pathways, and what the readouts tell us about where the field is heading. 7 pieces on drug development in Immunology, newest first within each collection.

Signals

7
SignalNEWMay 8, 2026

IgG4-related disease enters real prescribing territory

Inebilizumab IgG4-RD pivotal data, rituximab maintenance protocols, and structured diagnostic pathways are reshaping IgG4-related disease management.

TreatmentPipelineDiagnosisDrug development
SignalNEWMay 8, 2026

Systemic sclerosis therapy options mature past hematopoietic stem cell transplant

Tocilizumab and nintedanib in SSc-ILD, anifrolumab pivotal data, and emerging mechanism-targeted programs are reshaping systemic sclerosis management.

TreatmentPipelineDrug developmentPatient journey
SignalNEWMay 7, 2026

Giant cell arteritis therapy options widen past corticosteroids

Tocilizumab maturity, secukinumab pivotal data, and emerging mechanism-targeted programs are reshaping giant cell arteritis management.

TreatmentPipelinePatient journeyDrug development
SignalNEWMay 7, 2026

ANCA-associated vasculitis therapy options mature around avacopan

Avacopan commercial maturity, rituximab maintenance protocols, and emerging mechanism programs are restructuring ANCA-associated vasculitis management.

TreatmentPipelinePatient journeyDrug development
SignalNEWMay 5, 2026

Chimeric autoantibody receptor T cells enter pemphigus vulgaris

Desmoglein 3-targeted CAART cell therapy programs in pemphigus vulgaris are reading out as a precision approach to autoantibody-driven disease.

TreatmentPipelineBiomarkersDrug development
SignalNEWMay 5, 2026

Lupus nephritis therapy options mature past induction-and-maintenance

Voclosporin and belimumab in lupus nephritis plus emerging mechanism programs are restructuring induction and maintenance therapy.

TreatmentPipelinePatient journeyDrug development
SignalNEWMay 4, 2026

Sjogren disease therapy enters real prescribing territory

First positive pivotal readouts in Sjogren disease are establishing a category that has had no specific systemic therapy for decades.

TreatmentPipelineDiagnosisDrug development